As told to Kaitlin Sullivan Victor W. Weedn, forensic scientist at George Washington University: Sperm are hard to find under a microscope, so we use a special dye to turn the heads red and tails green. But the tails often break off, leaving the heads, which, unless carefully examined, look like totally different cells. To make sure we find the sperm, we take it slow. Nilay Yapici, neurobiologist at Cornell University: In an attempt to pinpoint a similar protein found in fruit flies and mosquitoes that could stop skeeters from biting, I genetically modified 400,000 flies and counted, by hand, millions of eggs. This was during graduate school in 2007, but manual tallying is still the quickest method. Ronald H. Towner, archaeological dendrochronologist at the University of Arizona: Tallying and measuring tree-ring widths helps archaeologists date ancient lumber. Computer programs often total the circles, but in dry places such as Arizona, drought years produce faint marks that only the human eye can discern. Daryll LaCourse, Amateur astronomer, Zooniverse, a citizen science project: I’m one of thousands of hobby scientists NASA commissioned to find exoplanets in data from the Kepler Telescope, which imaged more than half a million stars. Tiny variations among plotted points are planets in orbit, which computers can miss. We found about 4,000. Tonya Schoenfuss, Dairy Products specialist at the University of Minnesota: My lab uses titration (adding one solution, drop by drop, to another until they neutralize) to quantify the protein in cheese. The steps preceding titration are the longest. That includes boiling the cheese for hours in sulfuric acid to dissolve it. This article was originally published in the Summer 2019 Make It Last issue of Popular Science.