In the past few years, MRT has emerged as a viable treatment for mitochondrial diseases, congenital conditions that a mother passes on to her child caused by mutations that prevent mitochondria from producing enough energy to fuel the body’s cells. There are a few different versions of the procedure, but in essence scientists would replace a mother’s damaged mitochondrial DNA with that of another healthy woman in an egg, which would combine with a healthy sperm to create a viable embryo that could then be implanted in the mother....

In previous cases, patients cured of HIV had received bone marrow transplants from donors with a rare genetic mutation that makes immune cells naturally resistant to the virus. The American, anonymously identified as the City of Hope patient after the California hospital where he was treated, received a stem cell transplant in 2019 that also contained the same mutation. Although the results look promising, infectious disease scientists are hesitant to call stem cell or bone marrow transplants official cures for HIV....

As 9to5Mac explained yesterday, there are number of indications pointing towards a major announcement from Apple within months regarding an entirely new tech ecosystem based around a “realityOS” or “rOS.” Reports as far back as 2017 reveal the company has been hard at work on a new iOS-based operating system for its future AR and VR devices. Additionally, Apple may have recently filed trademarks for the names “Reality One” and “Reality Pro,” indicating potential products and/or new, dedicated processor chips for the devices....

Their 2021 update of its $103,200 F-Type two-seat sports car (the convertible version costs $105,900) is a glorious return to form for a company that built its reputation on the 24 Hours of Le Mans-winning performance of its D-Type, and the voluptuous styling of its E-Type. Carmakers like Jaguar, which enjoy the benefit of an illustrious heritage, risk being captured by that heritage and doomed to being thought of as “classics” even though they are new....

I’m a slave to the notification icon as much as anyone. In an ideal world, I’d learn to keep pushing forward and deal with email when I actually have time between other tasks. But that’s not as easy as it sounds. So instead of changing my own behavior, I’ve forced my inbox to do things my way so I spend less time emailing and more time working. Gmail has been a great ally in this, and the platform’s steady stream of new features has given me ever-increasing power to bend my inbox to my will....

Fortunately, modern-day operating systems come with a number of handy diagnostic tools that can give you more insight into how well (or how badly) your laptop or desktop is managing the strain. These can help you work out the root cause of a problem, warn you of potential issues, let you manage system resources more effectively, and even assist as you decide if it’s time to trade in your machine for a newer model....

The authors examined more than a dozen countries across western, eastern, and southern Africa and found that flooding can affect food security for over 5.6 million people across the continent. “Our findings show that floods can impact food security both immediately and in the months after the flood event,” Connor Reed, a former New York University Center for Data Science graduate student and lead author on the study, said in a press release....

The demonstrator in this video may lack stage presence, but the demonstration gets the point across pretty clearly. When you inject air bubbles into a fluid such as water, the mixture or air and water will have a reduced density compared to the density of water. The buoyancy of an object in a fluid depends on the density of the fluid. If the object has a lower density than the fluid, it will float; if less, it will sink....

Epic typically charges $9.99 for a grip of V-bucks, the game’s in-world currency, which players can use to buy aesthetic upgrades to their characters or dances. V-bucks can also buy Battle Pass subscriptions, which grant them extra XP and the chance to unlock game items. Last week, the company dropped the price to just $7.99 if you bought the currency straight through Epic’s systems rather than going through the App Store....

Thankfully for those who dressed as FBI agent Fox Mulder (David Duchovny) for Halloween (ahem), the show, a delightful dramedy that sprinkled conspiracy theory, aliens, and the paranormal weekly on Fridays, will return after a decade-plus hiatus. The show is set to air on Fox later this month for a six-episode miniseries, and critics and fans alike are highly anticipating where Mulder and agent Dana Scully (Gillian Anderson) will pick up....

The fully energized panel could have given Parazynski life-threatening electrical shocks out-of-reach of any hospital on Earth. For some, that level of risk would have been a segue to retirement. Not for Parazynski. “Best day on the job ever,” he told me recently, during a phone interview. I could hear him smiling. Parazynski just seems to be wired differently than many of us. His pursuit of extreme environments seems to know no bounds....

There is a commonsense rule about wild mushrooms that all outdoorsmen should heed: Avoid them. There are about 10,000 species of fungi out there, of which only a small number will kill you. From that vantage, the odds sound OK. Thing is, with the exception of a few easily identifiable species, it’s hard to tell the lethal from the good. And mushrooms have never been known for being forgiving. Often, as in the case of the aptly named death cap (Amanita phalloides), they look like a hundred other mushrooms, some of which are delicious....

What sets the Mojave apart, specifically, is that it’s designed outright as a short takeoff and landing plane, expanding the kinds of terrain it can operate from. “We are providing the ground force with a long-endurance, armed overwatch UAS [unmanned aerial system] that can quickly reload weapons at austere sites, located close to the conflict zone,” General Atomics aeronautical systems CEO Linden Blue said in a release. The Mojave comes 14 years after the Reaper entered service, and 27 years after the Predator first flew in 1994....

Apple users can access these services across their devices and share them with up to six family members. Even better, actions on these devices are private and secure, giving you peace of mind when it comes to your digital footprint and data. Apple TV+ allows you to stream Apple Original series and films on your television using an Apple TV or another Apple device using the Apple TV app. After the free trial, your plan automatically renews at $4....

To get started, head to Arduino’s software page and download the proper program for your system. If you’re using Windows 8.1, for example, install the “Windows Installer, for Windows XP and up.” Run the program, following on-screen prompts to give it permission to modify your system. You’ll also need: Arduino UnoUSB Type-A to USB Type-B connectorLED (optional) You can use an official Arduino board for this, or another compatible microcontroller, but we chose the Arduino Uno because it’s a common starter board for beginners and experienced programmers alike....

But the thing about iPhones is, well, the price point. They’ve only gotten more expensive over the years, so it’s hard to justify a purchase. But if you have someone on your list that wishes to find an iPhone under the tree, you can still fulfill their wish without breaking the bank by copping a refurbished one. For a limited time, you can score the black Apple iPhone XR on sale for less than $300....

Gifts for people you love Nothing says “this is forever” like an endless loop of photos. With Aura’s app for iOS and Android, you can wirelessly beam those better-off-deleted bachelor party pics, angelic images of chubby-cheeked babies, and everything else crowding your cloud right into this digital frame. This cute, comprehensive guide to houseplants will ensure you don’t destroy your love fern. With 100 plant profiles and gorgeous photography, it’s the white whale of coffee table books: good looking and something you actually want to crack open....

But the platform has been in the news lately for reasons relating to privacy and security, an issue that came to a head when President Trump issued an executive order on August 6 that outlaws transactions with TikTok’s parent company. (Read TikTok’s response here and an analysis of the head-scratching presidential decision here.) The drama stems from a fact that separates TikTok from other similar social media apps like Instagram: ByteDance, the company’s parent, is Chinese....

The 3rd-generation Apple AirPods are earbuds that offer advanced features that you won’t find in the AirPods 2 model. Those features include spatial audio with dynamic head-tracking to automatically adjust audio; an adaptive EQ system that tailors itself to your hearing; a sweat- and water-resistant design; and a long-lasting MagSafe Charging Case that brings total listening time up to 30 hours. All these upgrades are in addition to the namesake AirPod tech that has stuck around since the first model, like quick access to Siri, in-ear detection, and easy tap controls, plus that classic white exterior....

As of yet there are no documented cases of hackers holding a user ransom by his medical device, but experts are realizing that cyber security for medical devices—really anything connected to the Internet, including surgical robots—is lagging woefully behind the digital protection arming other systems and gadgets. Experts quoted in a recent piece in Bloomberg Business estimate that the security around medical devices is about a decade behind the overall standard....