First Video Of A Virus Being Born
Using a specialized technique called total internal reflection microscopy, the researchers were able to aim light at the cell at an angle which lit only the outermost surface, where HIV assembles. To be sure they were seeing actual viral assembly, they added fluorescent molecules to the Gag protein in the cell, which is essential to viral construction. When the proteins appeared at the surface of the cell, the fluorescence changed color as the molecules packed in more tightly, another indicator that what was being witnessed was in fact viral creation....